Statistical design and the analysis of gene expression microarray data
نویسندگان
چکیده
منابع مشابه
Statistical design and the analysis of gene expression microarray data.
Gene expression microarrays are an innovative technology with enormous promise to help geneticists explore and understand the genome. Although the potential of this technology has been clearly demonstrated, many important and interesting statistical questions persist. We relate certain features of microarrays to other kinds of experimental data and argue that classical statistical techniques ar...
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Most genomic data within the NextBio platform are generated using the Affymetrix platform (Figure 2). Ideally, all Affymetrix data would be imported as CEL files, and processed using the same normalization method, such as Robust Multi-array Average (RMA)1; however, for pre-existing experiments, this is often impossible. In this case, probeset-level Microarray Suite version 5 (MAS5) intensities2...
متن کاملData Analysis: Microarray Gene Expression
Most genomic data within the NextBio platform are generated using the Affymetrix platform (Figure 2). Ideally, all Affymetrix data would be imported as CEL files, and processed using the same normalization method, such as Robust Multi-array Average (RMA)1; however, for pre-existing experiments, this is often impossible. In this case, probeset-level Microarray Suite version 5 (MAS5) intensities2...
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15 صفحه اولAnalysis of microarray gene expression data
This article reviews the methods utilized in processing and analysis of gene expression data generated using DNA microarrays. This type of experiment allows to determine relative levels of mRNA abundance in a set of tissues or cell populations for thousands of genes simultaneously. Naturally, such an experiment requires computational and statistical analysis techniques. At the outset of the pro...
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ژورنال
عنوان ژورنال: Genetics Research
سال: 2007
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672308009713